Pregnancy Checks: Diagnostic pregnancy exams based upon immunological reactions amongst HCG and anti-HCG may well cause false-detrimental or Phony-optimistic interpretations.

Implement collaboration within just an interprofessional crew to develop thorough discomfort administration ideas that handle individual wants whilst reducing the risks connected to codeine use.

Promethazine with Codeine Oral Resolution is just not advisable to be used in Expecting Ladies [see Use in Certain Populations (8.one)]. Extended utilization of Promethazine with Codeine Oral Answer during pregnancy may end up in neonatal opioid withdrawal syndrome, which may be life-threatening if not acknowledged and taken care of, and calls for management according to protocols developed by neonatology professionals.

Combination prescription drugs that contains codeine, which include Those people coupled with other non-opioid suffering reduction medicines for example acetaminophen, have Program III to V classifications, which recommend small to average habit potential. Mixture hydrocodone items keep on being at Timetable II.

If a affected person needs a refill, reevaluate the cause of the cough and assess the necessity for continued therapy with Promethazine with Codeine Oral Solution, the relative incidence of adverse reactions, and the development of habit, abuse, or misuse.

Small children might be additional sensitive on the Unwanted effects of the drug, Particularly slowed respiration and uncontrolled actions (see also Warning part). Youngsters may also practical experience excitability instead of drowsiness.

urination problems, for example issues or ache when urinating or a rise in the frequency of urination

Codeine and hydrocodone may also connect with sedative drugs, Particularly benzodiazepines. Mixing these remedies can impact respiratory and will most likely be fatal. This mix was accountable for Practically fourteen% of overdose deaths involving opioids in 2021.

The next severe adverse reactions are described, Promethazine codeine syrup or described in higher depth, in other sections:

If this SPL contains inactivated NDCs stated because of the FDA initiated compliance action, They are going to be specified therefore.

Codeine is really a prodrug metabolized by cytochrome P450 2D6 to morphine which mediates many of the analgesic consequences of codeine in the body. In excess of 100 variants of this enzyme (CYP2D6) result in a continuum of exercise.

It is vital that your doctor Look at your or your child's progress whilst using this drugs. This allows your physician to find out if the drugs is Doing work appropriately and to come to a decision in the event you or your son or daughter really should continue to consider it. Blood checks may very well be needed to check for undesirable effects.

Applying Liquor or tobacco with certain medicines may lead to interactions to happen. The next interactions happen to be chosen on The idea of their opportunity importance and so are not essentially all-inclusive.

Take this medication only as directed by your medical professional. Usually do not just take additional of it, tend not to acquire it a lot more normally, and do not choose it for an extended time than your health care provider purchased.